• br AML therapies with curative intent br Alternative

  2019-06-27

  

  AML therapies with curative intent Alternative treatment strategies Targeted therapies: the new kids on the block The recognition of specific mutations as genetic drivers or facilitators of AML has led to the development of new inhibitors and targeted treatment options. New promising drug c

• Many of the emerging non vaccine serotypes in carriage after

  2019-06-27

  

  Many of the emerging non-vaccine serotypes in carriage after PCV13 implementation (11A, 15B/C, 15A, 21, 23B, and 35F) show low potential for causing invasive disease, but some—eg, 12F, 22F, 24F, 8, and 9N—have high disease potential. Moreover, in vulnerable populations (eg, immunocompromised people)

• br We have concerns about both the accuracy and

  2019-06-27

  

  We have concerns about both the accuracy and underlying rationale of Eugene Richardson and colleagues\' Comment about the “Ebola suspect\'s dilemma”. The authors quote a nosocomial infection rate of “around 25%” for individuals admitted to Ebola treatment facilities without Ebola virus disease. Ho

• NCS is a rare syndrome In

  2019-06-26

  

  NCS is a rare syndrome. In case series of NCS 14–47% were associated with of lymphoproliferative disorders [reviewed in [12]]. Survival is usually dictated by the underlying disease and short in the setting of aggressive malignancies. Since NCS may be a manifestation of an underlying malignancy it h

• br Conclusion br Authors contribution br

  2019-06-26

  

  Conclusion Authors’ contribution Competing interests Acknowledgments Case report Imatinib has radically changed prognosis in chronic-phase Chronic Myeloid Leukemia (CML), with 90% overall survival rate at 8yrs, and 40–70% of patients achieving a stable MMR [1]. Even better results hav

• Interpretation Patient centred medical education can improve

  2019-06-26

  

  Interpretation Patient-centred medical education can improve overall satisfaction and sustained disease-specific knowledge in patients in Uganda. Our results show that printed booklets are accepted by patients and feasible to implement in a LMIC outpatient setting. Funding Trishul Siddharthan recei

• Previous health emergencies have shown that

  2019-06-26

  

  Previous health emergencies have shown that it can take time to organise global collective action and provide financing to the national and local level. In such situations, a global mechanism should offer a rapid injection of liquidity to affected countries. The World Bank\'s Pandemic Emergency Fina

• br Historical overview Before the development of

  2019-06-26

  

  Historical overview Before the development of screw-in leads, several types of non-screw pacing leads were designed to passively attach to the EMD-1214063 muscle with tips of different shapes, including straight, fringed, finned, or tined. However, a high incidence of dislodgement was a major con

• Most women were found to be unaware of

  2019-06-26

  

  Most women were found to be unaware of possible prevention of the disease, including screening services for early detection and treatment of precancerous lesions. Some women affected by CC tend to initially seek treatment from traditional healers and use holy water. Beliefs concerning the cause of t

• Introduction Several types of cancers including those origin

  2019-06-26

  

  Introduction Several types of cancers, including those originating in the breast, prostate, and lung, have a propensity to metastasize to the bones [1,2]. Bone metastases severely impair skeletal metabolism, and result in important clinical sequelae, such as excruciating chronic bone pain and the s

• Mizoribine what Numerous animal studies have demonstrated be

  2019-06-26

  

  Numerous animal studies have demonstrated beyond doubt that effective inhibition of osteoclastogenesis or osteoclast function significantly reduces metastatic tumour growth in bone [13–20]. Likewise, clinical trials in patients with non-metastatic or metastatic cancers established that treatment wit

• br Conclusion br Limitations br Conflict

  2019-06-26

  

  Conclusion Limitations Conflict of interest Introduction The prevalence of Talarozole weight failure prevalence is increasing throughout the world. The reasons for this pandemic include the aging populations of both industrialized and developing nations and a growing incidence of obesit

• En el encuentro con la prima Isabel

  2019-06-26

  

  En el encuentro con la prima, Isabel, los dos rivales conocen también Pridinol Methanesulfonate of Clemencia , cuya presencia inicia una conversación entre los dos hombres. Es una escena esencial a la hora de examinar la relación de rivalidad entre ellos dos. Primero, discuten quién va a estar con q

• Expansion of access to HIV treatment is a global

  2019-06-26

  

  Expansion of access to HIV treatment is a global priority. In July, 2013, UNAIDS, in collaboration with WHO, the Global Fund to fight AIDS, Tuberculosis and Malaria, and the US President\'s Emergency Plan for AIDS Relief (PEPFAR) jointly issued which advocates for a worldwide treatment target of 15

• br Chronic obstructive pulmonary disease COPD remains a

  2019-06-26

  

  Chronic obstructive pulmonary disease (COPD) remains a major public health problem. The was first published by the Global Initiative for Chronic Obstructive Lung Disease (GOLD) in 2001. A major revision was undertaken in 2011 and an update to it was published in February this year. The Chinese Soc

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