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br Discussion ATRA and arsenic are both known to
2019-06-24
Discussion ATRA and arsenic are both known to induce differentiation syndrome but this case was notable for its severity. Previous studies of differentiation syndrome have demonstrated that APL LY2603618 treated with ATRA secrete the chemokines CCL2 and IL-8, which in combination with chemokine
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Frustratingly in the past years the world
2019-06-24
Frustratingly, in the past 40 years the world has added only two new drugs to the arsenal against tuberculosis, the second most deadly infectious disease on the planet. The statistics are infuriating: more than 9 million people developed tuberculosis in 2013, and an estimated 44% of those in countri
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An imperative need now exists for new thinking increased res
2019-06-24
An imperative need now exists for new thinking, increased resources, and better training of health-care staff working with these new populations. At a time when there is a danger of religiopolitical extremism in the wake of perceived (and sometimes real) antipathy to newcomers, the health sector has
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The lack of a single identified correlate of
2019-06-24
The lack of a single identified correlate of protection for LAIV should not deter future immunogenicity studies in resource-limited settings, especially using systems vaccinology approaches designed to dissect the complex interplay of innate and adaptive pathways following vaccination. John C Victor
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br Discussion Variant angina was described by Prinzmetal
2019-06-24
Discussion Variant Sulfamethazine was described by Prinzmetal et al. in 1959 [1]. It can involve serious arrhythmias such as ventricular tachycardia, ventricular fibrillation, and atrioventricular block, and patients are particularly susceptible to sudden cardiac death in such cases [2,3]. Coron
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br Mega cohort studies Remote monitoring
2019-06-24
Mega-cohort studies Remote monitoring collects a wealth of data from large numbers of patients which are not subject to saturation or overwritten memory counters within any implantable device. These databases provide an opportunity to better understand system function, patient condition, and dise
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br Conclusions br Source of funding br
2019-06-21
Conclusions Source of funding Conflict of interest Acknowledgments Introduction Atrial fibrillation (AF) is an arrhythmia that is commonly seen and occurs more often in the elderly. In Japan, the overall prevalence of all types of AF based on the data from periodic health examinations
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Esta subalternidad por ende no tiene referente estable pero
2019-06-21
Esta subalternidad, por ende, no tiene referente estable pero tampoco es una abstracción relativa, de manera que los grupos reprimidos históricamente, entre ellos ciertas razas, proveen ejemplos ineludibles pero no exentos de su propio exceso. De manera que todo planteamiento anclado en la identidad
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En el documental Tacos altos
2019-06-21
En el documental Tacos altos en el barro (Rolando Pardo, 2014), una de las travestis afirma que “somos seres humanos igual que ustedes”, mientras se esparce una crema por su rostro, rodeado de carencias económicas y de infraestructura de todo tipo. Esta cinta se ocupa de la relación entre prostituci
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br Introduction Since Reekers and Bolia
2019-06-21
Introduction Since Reekers and Bolia introduced subintimal angioplasty, the trans-subintimal route has become the preferred technique to advance the guidewire through a totally occluded and often heavily calcified lesion, especially in the aortoiliac segment. The technical failure was seen in 20–
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br Conflict of interest br Acknowledgments The project
2019-06-21
Conflict of interest Acknowledgments The project has been supported by grants from Science Foundation Ireland, Ireland (Starting Investigator Research Grant to ES, 09/SIRG/B1575, TIDA to ES 12/TIDA/B2388) and by the Millennium Fund of NUIG. The t(3;21)(q26;q22) is a rare cytogenetic abnorma
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An interesting finding in the study of
2019-06-21
An interesting finding in the study of Ngabo and colleagues was that, after a huge drop in the number of admittances to hospital for rotavirus in 2013, there was no further fall the next year. As the researchers discuss, this finding might herald the beginning of a biennial pattern of rotavirus acti
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A substantial part of the value of
2019-06-21
A substantial part of the value of setting goals, targets, and indicators lies in the imperative to collect information for measurement and accountability —“what gets measured gets done”. The decision to exclude an indicator because it Bradykinin acetate is less established is diametrically opposed
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Adenosine-5\'-diphosphate Two fundamental objections to
2019-06-21
Two fundamental objections to the conclusion that mass deworming for helminths has no benefits and could therefore be abandoned have been repeatedly raised. First, the underlying studies might have been insufficient to detect benefits, because the follow-up for most studies was too short to detect
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Conessine IL can induce phagocytosis cytoskeleton rearrangem
2019-06-21
IL-15 can induce phagocytosis, cytoskeleton rearrangement, gene expression, de novo protein synthesis and can delay apoptosis in human neutrophils [15]. Production of chemokines, cytokines and natural inhibitors is increased in IL-15 induced neutrophils, including CXCL8 (IL-8) [16], IL-1beta, IL-1RI
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