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Atrial fibrosis is one of the fundamental mechanisms
2019-06-21

Atrial fibrosis is one of the fundamental mechanisms for the pathogenesis of atrial fibrillation (AF), but the underlying electrophysiological changes involved are not completely understood. Aging, neurohumoral activation, and chronic atrial stretch due to structural heart disease activate various s
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Cardiac fibroblasts express various ion channels
2019-06-21

Cardiac fibroblasts express various ion channels, in particular voltage-gated K nitric oxide synthase inhibitors and nonselective cation channels of the transient receptor potential (TRP) family . Both K and TRP channels are important determinants of fibroblast function, with TRP channels acting as
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order BINA The re treatment of metastatic
2019-06-21

The re-treatment of metastatic bone disease causing recurrent pain after an initial course of EBRT was seen to be feasible with a reasonable rate of symptom relief [13–19]. In echoing the ACR findings, the task force noted that the available data was derived from studies where re-treatment was not t
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Recogiendo en el cap tulo
2019-06-21

Recogiendo en el capítulo siguiente del libro (“La fenomenología del instante en ”, 147–161) lo que al final del anterior ha dicho sobre , Escalante propone, partiendo de la distinción entre descripción fenomenológica e interpretación, puesta, empero, en tela de juicio por Heidegger (148), que el “n
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Sadly cytomegalovirus retinitis remains the neglected diseas
2019-06-21

Sadly, cytomegalovirus retinitis remains the neglected disease of the AIDS pandemic, and there is an increasing group of young patients in low-income and middle-income countries made healthy by successful treatment of underlying HIV, yet left permanently blind from undiagnosed or inadequately treate
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KN-93 Phosphate br The L type calcium channel LTCC
2019-06-20

The L-type calcium channel (LTCC) in heart consists of 4 subunits: α1, β2, α2, and δ [47], encoded by CACNA1C, CACNB2, and CACNA2D, respectively, with the α2 and δ subunits encoded by the gene CANA2D. In 2007, Antzelevitch et al. [48] reported 2 CACNA1C mutations and a CACNB2 mutation from a genot
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br Do we need complete
2019-06-20

Do we need complete isolation of all PVs in every patient? Circumferential PVI results in satisfactory outcomes for ablation of paroxysmal AF, and electrical isolation of all PVs is currently a standard approach to the treatment of AF, as recommended by the expert consensus statement [6]. Complet
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A 804598 The final variant deals with
2019-06-20

The final variant deals with a patient who has a poor prognosis due to visceral metastases and who suffers from a single site of painful bone disease. The purpose of the case was to evaluate the panel\'s views of supportive care with analgesic medications plus or minus EBRT. The group did recommend
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TP-0903 br Materials and methods Fifteen
2019-06-20

Materials and methods Fifteen healthy adult men participated in this study. The left anterior chest area was subdivided into 15 regions based on 5 longitudinal points (from the second to the sixth intercostal spaces) and 3 lateral points (including the left sternal border, midclavicular line, and
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The ETV ABL fusion has been
2019-06-20

The ETV6-ABL1 fusion has been reported as a poor prognostic factor when found in acute leukemia (AML and ALL) and MDS. The prognostic significance of an ETV6/ABL1 chronic myeloproliferative neoplasm is less clear due to the paucity of cases and the lack of controlled clinical trials [5]. There is a
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The number of residents in London who were originally
2019-06-20

The number of residents in London who were originally from the 21 endemic countries in Central and South America was calculated from the 2011 UK National Census and was stratified by borough. We did not include undocumented migrants and individuals born to mothers from endemic Latin American countri
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Friberg et al have indicated that
2019-06-20

Friberg et al. [17] have indicated that the CHA2DS2-VASc score is superior to the CHADS2 score in terms of stroke risk stratification, and the risk of stroke is extremely low among patients with a CHA2DS2-VASc score of 0 in whom antithrombotic therapy is not beneficial and may even increase the risk
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glucagon receptor Catheter ablation of a concealed right ant
2019-06-20

Catheter ablation of a concealed right anteroseptal AV bypass tract was successfully performed in our patient. Catheter ablation of the anteroseptal accessory pathway did not affect normal AV conduction. The effective refractory period of the fast AV node was 380ms at a pacing glucagon receptor len
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There has been scant prior research focusing on the
2019-06-20

There has been scant prior research focusing on the clinical efficiency and safety of either BV alone or in combination with chemotherapy in treating relapsed or refractory CD30+ T cell lymphoma, ALCL and HL. Although the most common and significant adverse events of BV, such as peripheral neuropath
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br Acknowledgments The authors would like to thank Sarah
2019-06-20

Acknowledgments The authors would like to thank Sarah Mack for technical assistance with the histology and IHC. We would also like to acknowledge Dr. Gregory Dieudonne in the Department of Musculoskeletal Radiology, University of Rochester Medical Center for advice and assistance in manuscript wr
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